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Otud6a c-myc

WebBased on this result, OTUD6A was chosen as a final candidate DUB and subjected to the subsequent experiments. Int. J. Mol. Sci. 2024, 22, x FOR PEER REVIEW 4 of 13 Figure 2. … WebJan 16, 2024 · (c) Schematic representation of full-length (FL) and truncated mutants of Aurora-A. (d) SFB-tagged OTUD6A was co-transfected with MYC-tagged full length or …

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WebMYC is an oncogenic transcription factor which is encoded by the c-myc proto-oncogene. By regulating target gene expressions, MYC has diverse roles involved in cell growth, … WebEfficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine model and a Phase I safety study in humans. Clin Cancer Res. 2003;9(7): 2510-9. … gabarit clown pantin https://benevolentdynamics.com

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Web#Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc ... WebMYC drives the tumorigenesis of human cancers, including prostate cancer (PrCa), thus deubiquitinase (DUB) that maintains high level of c-Myc oncoprotein is a rational … WebMyc-tag. A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used for affinity … gabarit clown sans cheveux

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Category:MYC - Overview: MYC Immunostain, Technical Component Only

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Otud6a c-myc

MYC - Overview: MYC Immunostain, Technical Component Only

WebLentivirus with CMV promoter-driven expression of OTU domain containing 6A (OTUD6A) in pLenti vector with puromycin selection and C-terminal Myc and FLAG tags. The store will … WebA tag already exists with the provided branch name. Many Git commands accept both tag and branch names, so creating this branch may cause unexpected behavior.

Otud6a c-myc

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WebApr 10, 2024 · Moreover, only OTUD6B but no other OTU family members was able to regulate β-TrCP, since knock down OTUD6A or OTUD2 did not increase β-TrCP protein level in ESCC cells (Figure S1E–H, Supporting Information). A cycloheximide (CHX) pulse-chase experiment was then performed to confirm that OTUD6B stabilizes the β-TrCP protein. WebMar 21, 2024 · An important paralog of this gene is OTUD6A. UniProtKB/Swiss-Prot Summary for OTUD6B Gene [Isoform 1]: ... Influences the expression of CCND1/cyclin D1 …

WebJan 1, 2024 · In this study, we found that OTUD6A is a physiological deubiquitinase for c-Myc in prostate cancer setting and promotes prostatic tumorigenesis through stabilizing … WebFeb 26, 2024 · Online ahead of print.ABSTRACTMYC drives the tumorigenesis of human cancers, including prostate cancer (PrCa), thus deubiquitinase (DUB) that maintains high …

Web2. Faria M, Khayat A, Burbano R, Rabenhorst SH: c-MYC amplification and expression in astrocytic tumors. Acta Neuropathol. 2008;116:87-95. 3. Ruzinova M, Caron T, Rodig S: … WebMYC (MYC proto-oncogene) is a transcriptional factor and oncoprotein. c-myc is a member of MYC gene family. It is located on human chromosome 8q24. c-Myc gene codes for basic helix-loop-helix/leucine zipper (bHLH/LZ) transcription factor. Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of …

WebJul 5, 2004 · C-myc protein Imported. Gene names. Name. c-myc Imported. Organism names. Organism. Homo sapiens (Human) Imported. Taxonomic identifier. 9606 NCBI. …

WebMyc is a family of regulator genes and proto-oncogenes that code for transcription factors.The Myc family consists of three related human genes: c-myc (), l-myc (), and n … gabarit ficheWebMar 1, 2024 · Furthermore, the interaction of OTUD6A with Brg1 and AR was also verified in other prostate cancer cell lines, including PC-3, LNCaP, and C4-2 cells, through IP-IB … gabarit clown à imprimerWebFeb 25, 2024 · Genetic ablation of OTUD6A efficiently repressed prostatic tumorigenesis of both human prostate cancer (PrCa) cells and the Hi-Myc transgenic PrCa mice, via … gabarit facebookWebbpg致力于知识的发现和传播 关于本刊; 在线投稿; 当前目次; 文献检索; 期刊首页 gabarit division 3 chiffresWebThe proteasome is a complex molecular machine degrades proteins after they are bound to ubiquitin. 18 Ubiquitin can be degraded by proteasome via its conjugated substrate when extended with a C-terminal tail and as a monomer. 19 Furthermore, disorders of ubiquitination and deubiquitination can lead to various diseases. 20 Masclef et al. … gabarit fiche recetteWebThe Human c-Myc Total (Hu c-Myc) ELISA quantitates Hu c-Myc in human cell lysates. The assay will exclusively recognize both natural and recombinant Hu c-Myc, independed of … gabarit division 2 chiffresWebMar 5, 2024 · Full-length p53 cDNA was subcloned into pcDNA3-HA vector from a pcDNA3-Myc-p53 vector used in our previous ... (B and C) The mRNA expression levels of (B) USP5 … gabarit fantôme halloween à imprimer