WebBackground One of the challenges in the interpretation of studies showing associations between environmental and genotypic data with disease outcomes such as … WebHtrA is responsible for disrupting the lateral junctions between epithelial cells. The mechanism by which C. jejuni opens tight junctions is yet unknown. For both pathogens, …
HtrA protease family as therapeutic targets. Semantic Scholar
Web9 dec. 2024 · Anti-Infective Agents HtrA Protease Family as Therapeutic Targets Current Pharmaceutical Design Novel Antimicrobial Agents Against Multi-drug-resistant Gram-positive Bacteria: An Overview Recent Patents on Anti-Infective Drug Discovery Management of Asymptomatic Severe Aortic Stenosis Web18 sep. 2012 · HtrA1 is a member of HtrA family proteins that are distributed in a range of species from bacteria, yeast, and plants to humans. 7, 9 Bacterial HtrAs are heat shock … two step verification sharefile
IJMS Free Full-Text Alpha-1 Antitrypsin-Induced Endoplasmic ...
WebThe so-called alkylphospholipid analogs (APLs) constitute a family of synthetic antitumor compounds that target cell membranes. The ether phospholipid edelfosine has been considered the long-standing prototype of these antitumor agents and promotes apoptosis in tumor cells by a rather selective way, while sparing normal cells. Increasing evidence … WebCompositions and methods of the present invention relating to B. burgdorferi HtrA sensu lato (BbHtrA) protease activity, its substrates, cleavage products, biological effects and … Web1 mei 2013 · The high-temperature requirement serine protease (HTRA) family constitutes a well-conserved group of proteolytic enzymes (HTRA1, 2, 3, and 4), having key roles in protein quality control as well as in the regulation of various signaling pathways through the degradation of specific substrates. 1, 2 Of the four known members, HTRA1 and -2 are … tall rock windclan